Secondary use of clinical trials data in health research: A Practical Guide
This document presents a theoretical framework for the use of clinical trials and other health data for secondary research purposes, which was derived from research papers, consultation with stakeholders and the research community. Four overall scenarios for data reuse were identified; scenario...
Keywords: Secondary Data Use, Clinical Trials, Training Material, HeSANDA, Health Data Australia, HDA
Secondary use of clinical trials data in health research: A Practical Guide
https://zenodo.org/records/12768050
https://dresa.org.au/materials/secondary-use-of-clinical-trials-data-in-health-research-a-practical-guide
This document presents a theoretical framework for the use of clinical trials and other health data for secondary research purposes, which was derived from research papers, consultation with stakeholders and the research community. Four overall scenarios for data reuse were identified; scenario 1: evidence synthesis, scenario 2: secondary analyses, scenario 3: reproducibility, replication and validation, and scenario 4: education and methods development.
contact@ardc.edu.au
Hunter, Kylie (orcid: 0000-0002-2796-9220)
Williams, Jonathan
Palacios, Talia
Tan, Aidan
Robledo, Kristy (orcid: 0000-0003-0213-7652)
Tjokrowidjaja, Angelina (orcid: 0009-0004-6570-9683)
Gouda-Vossos, Amany (orcid: 0000-0002-6142-9439)
Kang, Kristan (orcid: 0000-0002-2057-1033)
Seidler, Anna Lene (orcid: 0000-0002-0027-1623)
Secondary Data Use, Clinical Trials, Training Material, HeSANDA, Health Data Australia, HDA
HeSANDA & Health Data Australia FAQ
This document provides answers to common questions about the Health Studies Australian National Data Asset (HeSANDA), and the Health Data Australia (HDA), including the usage of the health data platform, sharing, contributing and accessing clinital trails data, governance, and potential risks.
Keywords: HeSANDA, Frequently asked Questions, Health Data Australia, training material
HeSANDA & Health Data Australia FAQ
https://zenodo.org/records/11075589
https://dresa.org.au/materials/hesanda-health-data-australia-faq
This document provides answers to common questions about the Health Studies Australian National Data Asset (HeSANDA), and the Health Data Australia (HDA), including the usage of the health data platform, sharing, contributing and accessing clinital trails data, governance, and potential risks.
contact@ardc.edu.au
Australian Research Data Commons
Australian Research Data Commons (type: Editor)
Australian Clinical Trials Alliance (type: Editor)
Melbourne Academic Centre for Health (type: Editor)
Mental Health Node (type: Editor)
The Queensland Node (type: Editor)
Sydney Health Partners Node (type: Editor)
Western Australia Node (type: Editor)
Monash University and Monash Partners Node (type: Editor)
Health Translation South Australia (type: Editor)
National Cancer Cooperative Trials Groups (type: Editor)
Northern Australia Node (type: Editor)
HeSANDA, Frequently asked Questions, Health Data Australia, training material
HeSANDA Monash Node User Guides
This guide developed by the HeSANDA Monash node provides an overview for users of Health Data Australia (HDA).
HDA helps researchers discover and access health data. HDA is a registry and does not store the data itself but provides descriptions of the data from data owners' publishing partners....
Keywords: Health Data Australia, health data, data request, HDA, HeSANDA, data access
HeSANDA Monash Node User Guides
https://zenodo.org/records/10275253
https://dresa.org.au/materials/hesanda-monash-node-user-guides
This guide developed by the HeSANDA Monash node provides an overview for users of Health Data Australia (HDA).
HDA helps researchers discover and access health data. HDA is a registry and does not store the data itself but provides descriptions of the data from data owners' publishing partners. Using HDA, researchers can search these descriptions, find data of use to do their research, then request access to it. The request will be sent to the owner of the data to review. Data owners receive email notifications about new data requests and can then log into the HDA Data Request platform to review the request and determine whether access can be granted and then respond to the researcher requesting access. If the request is approved, the owner arranges for the researcher to be given access to the data.
The dataset descriptions (‘metadata’) contained on HDA help researchers understand the kinds of data that exist and assess whether a dataset may be of value to their research, without the need to actually access the data. In addition to metadata, data owners provide other documentation describing the data they hold, such as study protocols and data dictionaries.
Using HDA, researchers can search for data, save their searches, submit and manage data requests.
Amany.Gouda-Vossos@ardc.edu.au
Monash Partners
Monash University
Health Data Australia, health data, data request, HDA, HeSANDA, data access
WEBINAR: Detection of and phasing of hybrid accessions in a target capture dataset
This record includes training materials associated with the Australian BioCommons webinar ‘Detection of and phasing of hybrid accessions in a target capture dataset’. This webinar took place on 10 June 2021.
Hybridisation plays an important role in evolution, leading to the exchange of genes...
Keywords: Phylogenetics, Bioinformatics, Phylogeny, Genomics, Target capture sequencing
WEBINAR: Detection of and phasing of hybrid accessions in a target capture dataset
https://zenodo.org/records/5105013
https://dresa.org.au/materials/webinar-detection-of-and-phasing-of-hybrid-accessions-in-a-target-capture-dataset-51cc7740-0da1-45f1-95de-f1a47f676053
This record includes training materials associated with the Australian BioCommons webinar ‘Detection of and phasing of hybrid accessions in a target capture dataset’. This webinar took place on 10 June 2021.
Hybridisation plays an important role in evolution, leading to the exchange of genes between species and, in some cases, generate new lineages. The use of molecular methods has revealed the frequency and importance of reticulation events is higher than previously thought and this insight continues with the ongoing development of phylogenomic methods that allow novel insights into the role and extent of hybridisation. Hybrids notoriously provide challenges for the reconstruction of evolutionary relationships, as they contain conflicting genetic information from their divergent parental lineages. However, this also provides the opportunity to gain insights into the origin of hybrids (including autopolyploids).
This webinar explores some of the challenges and opportunities that occur when hybrids are included in a target capture sequence dataset. In particular, it describes the impact of hybrid accessions on sequence assembly and phylogenetic analysis and further explores how the information of the conflicting phylogenetic signal can be used to detect and resolve hybrid accessions. The webinar showcases a novel bioinformatic workflow, HybPhaser, that can be used to detect and phase hybrids in target capture datasets and will provide the theoretical background and concepts behind the workflow.
This webinar is part of a series of webinars and workshops developed by the Genomics for Australian Plants (GAP) Initiative that focuses on the analysis of target capture sequence data. In addition to two public webinars, the GAP bioinformatics working group is offering training workshops in the use of newly developed and existing scripts in an integrated workflow to participants in the 2021 virtual Australasian Systematic Botany Society Conference.
The materials are shared under a Creative Commons 4.0 International agreement unless otherwise specified and were current at the time of the event.
Files and materials included in this record:
Event metadata (PDF): Information about the event including, description, event URL, learning objectives, prerequisites, technical requirements etc.
Index of training materials (PDF): List and description of all materials associated with this event including the name, format, location and a brief description of each file.
Nauheimer_hybphaser_slides (PDF): Slides presented during the webinar
Materials shared elsewhere:
A recording of the webinar is available on the Australian BioCommons YouTube Channel: https://youtu.be/japXwTAhA5U
Melissa Burke (melissa@biocommons.org.au)
Nauheimer, Lars (orcid: 0000-0002-2847-0966)
Phylogenetics, Bioinformatics, Phylogeny, Genomics, Target capture sequencing
WEBINAR: Conflict in multi-gene datasets: why it happens and what to do about it - deep coalescence, paralogy and reticulation
This record includes training materials associated with the Australian BioCommons webinar ‘Conflict in multi-gene datasets: why it happens and what to do about it - deep coalescence, paralogy and reticulation’. This webinar took place on 20 May 2021.
Multi-gene datasets used in phylogenetic...
Keywords: Phylogenetics, Bioinformatics, Phylogeny, Genomics, Target capture sequencing
WEBINAR: Conflict in multi-gene datasets: why it happens and what to do about it - deep coalescence, paralogy and reticulation
https://zenodo.org/records/5104998
https://dresa.org.au/materials/webinar-conflict-in-multi-gene-datasets-why-it-happens-and-what-to-do-about-it-deep-coalescence-paralogy-and-reticulation-a6743550-b904-45e1-9635-4e481ee8f739
This record includes training materials associated with the Australian BioCommons webinar ‘Conflict in multi-gene datasets: why it happens and what to do about it - deep coalescence, paralogy and reticulation’. This webinar took place on 20 May 2021.
Multi-gene datasets used in phylogenetic analyses, such as those produced by the sequence capture or target enrichment used in the Genomics for Australian Plants: Australian Angiosperm Tree of Life project, often show discordance between individual gene trees and between gene and species trees. This webinar explores three different forms of discordance: deep coalescence, paralogy, and reticulation. In each case, it considers underlying biological processes, how discordance presents in the data, and what bioinformatic or phylogenetic approaches and tools are available to address these challenges. It covers Yang and Smith paralogy resolution and general information on options for phylogenetic analysis.
This webinar is part of a series of webinars and workshops developed by the Genomics for Australian Plants (GAP) Initiative that focused on the analysis of target capture sequence data. In addition to two public webinars, the GAP bioinformatics working group is offering training workshops in the use of newly developed and existing scripts in an integrated workflow to participants in the 2021 virtual Australasian Systematic Botany Society Conference.
The materials are shared under a Creative Commons 4.0 International agreement unless otherwise specified and were current at the time of the event.
Files and materials included in this record:
Event metadata (PDF): Information about the event including, description, event URL, learning objectives, prerequisites, technical requirements etc.
Index of training materials (PDF): List and description of all materials associated with this event including the name, format, location and a brief description of each file.
Schmidt-Lebuhn - paralogy lineage sorting reticulation - slides (PDF): Slides presented during the webinar
Materials shared elsewhere:
A recording of the webinar is available on the Australian BioCommons YouTube Channel: https://youtu.be/1bw81q898z8
Melissa Burke (melissa@biocommons.org.au)
Schmidt-Lebuhn, Alexander (orcid: 0000-0002-7402-8941)
Phylogenetics, Bioinformatics, Phylogeny, Genomics, Target capture sequencing
DReSA: Project team reflections
This presentation provides thoughts and reflections from the Digital Research Skills Australaisa (DReSA) project team on DReSA. Team members highlight their perspectives on value propositions and benefits for their respective institutiosn/organisations and nationally, as well as individual...
Keywords: training events, training material, training repository, skilled workforce, digital research skills, digital research training, digital research, trainers, FAIR training
DReSA: Project team reflections
https://zenodo.org/records/5712129
https://dresa.org.au/materials/dresa-project-team-reflections-9dcb8538-6b7c-4822-b0ee-fbe57085dc70
This presentation provides thoughts and reflections from the Digital Research Skills Australaisa (DReSA) project team on DReSA. Team members highlight their perspectives on value propositions and benefits for their respective institutiosn/organisations and nationally, as well as individual reflections on collaboration and working together on the project so far.
You can watch the video on YouTube here: https://youtu.be/qqH92itI8SI
contact@ardc.edu.au
Unsworth, Kathryn (orcid: 0000-0002-5407-9987)
Papaioannou, Anastasios (orcid: 0000-0002-8959-4559)
Backhaus, Ann (orcid: 0000-0002-9023-055X)
Vanichkina, Darya (orcid: 0000-0002-0406-164X)
Symon, Jon
Steel, Kay (orcid: 0000-0002-5720-1239)
Burke, Melissa (orcid: 0000-0002-5571-8664)
May, Nick
training events, training material, training repository, skilled workforce, digital research skills, digital research training, digital research, trainers, FAIR training
HeSANDA Monash Node Workshop Content
Slide presentation for a HeSANDA workshop delivered on January 1, 2023, which provides the audience with a broad understanding of the HeSANDA program, including Health Data Australia (HDA).
What is HeSANDA:
The Health Studies Australian Data Asset (HeSANDA) is a national program that makes...
Keywords: health data, clinical trials, HeSANDA, Health Data Australia
HeSANDA Monash Node Workshop Content
https://zenodo.org/records/10275272
https://dresa.org.au/materials/hesanda-monash-node-workshop-content
Slide presentation for a HeSANDA workshop delivered on January 1, 2023, which provides the audience with a broad understanding of the HeSANDA program, including Health Data Australia (HDA).
What is HeSANDA:
The Health Studies Australian Data Asset (HeSANDA) is a national program that makes health and medical research data easier to find. It facilitates access, sharing and reuse of research data. This results in a reduction in research waste, improvements in researcher collaboration, and an opppotunity ti answer new research questions. It aims to support more efficitent and effective research to help improve health outcome.
Amany.Gouda-Vossos@ardc.edu.au
Monash Partners
Monash University
health data, clinical trials, HeSANDA, Health Data Australia
"How To" Video Guide for the Australian Child and Youth Wellbeing Atlas
This "How To" Video Guide for the Australian Child and Youth Wellbeing Atlas covers key features, step-by-step instructions, and screen shots. It assists users in navigating the data platform with 400+ data sets on children and young people's health and wellbeing. The platform offers geospatial...
Keywords: research data, digital research skills, health data, digital research training, Community Connect, ARDC
"How To" Video Guide for the Australian Child and Youth Wellbeing Atlas
https://australianchildatlas.com/acywa-resources
https://dresa.org.au/materials/how-to-video-guide-for-the-australian-child-and-youth-wellbeing-atlas
This "How To" Video Guide for the Australian Child and Youth Wellbeing Atlas covers key features, step-by-step instructions, and screen shots. It assists users in navigating the data platform with 400+ data sets on children and young people's health and wellbeing. The platform offers geospatial visualisations and maps at various geographic levels.
A/Prof Rebecca Glauert, UWA,
Marketa Reeves, UWA
research data, digital research skills, health data, digital research training, Community Connect, ARDC
User Manual for the Australian Child and Youth Wellbeing Atlas
This user manual for the Australian Child and Youth Wellbeing Atlas covers key features of the platform, step-by-step instructions, and screen shots. It assists users in navigating the data platform with 400+ data sets on children and young people's health and wellbeing. The platform offers...
Keywords: research data, health data, digital research skills, digital research training, Community Connect, ARDC
User Manual for the Australian Child and Youth Wellbeing Atlas
https://australianchildatlas.com/s/Atlas-platform-user-guide.pdf
https://dresa.org.au/materials/user-manual-for-the-australian-child-and-youth-wellbeing-atlas
This user manual for the Australian Child and Youth Wellbeing Atlas covers key features of the platform, step-by-step instructions, and screen shots. It assists users in navigating the data platform with 400+ data sets on children and young people's health and wellbeing. The platform offers geospatial visualisations and maps at various geographic levels.
A/Prof Rebecca Glauert, UWA,
Marketa Reeves, UWA
research data, health data, digital research skills, digital research training, Community Connect, ARDC
WEBINAR: Detection of and phasing of hybrid accessions in a target capture dataset
This record includes training materials associated with the Australian BioCommons webinar ‘Detection of and phasing of hybrid accessions in a target capture dataset’. This webinar took place on 10 June 2021.
Hybridisation plays an important role in evolution, leading to the exchange of genes...
Keywords: Phylogenetics, Bioinformatics, Phylogeny, Genomics, Target capture sequencing
WEBINAR: Detection of and phasing of hybrid accessions in a target capture dataset
https://zenodo.org/record/5105013
https://dresa.org.au/materials/webinar-detection-of-and-phasing-of-hybrid-accessions-in-a-target-capture-dataset
This record includes training materials associated with the Australian BioCommons webinar ‘Detection of and phasing of hybrid accessions in a target capture dataset’. This webinar took place on 10 June 2021.
Hybridisation plays an important role in evolution, leading to the exchange of genes between species and, in some cases, generate new lineages. The use of molecular methods has revealed the frequency and importance of reticulation events is higher than previously thought and this insight continues with the ongoing development of phylogenomic methods that allow novel insights into the role and extent of hybridisation. Hybrids notoriously provide challenges for the reconstruction of evolutionary relationships, as they contain conflicting genetic information from their divergent parental lineages. However, this also provides the opportunity to gain insights into the origin of hybrids (including autopolyploids).
This webinar explores some of the challenges and opportunities that occur when hybrids are included in a target capture sequence dataset. In particular, it describes the impact of hybrid accessions on sequence assembly and phylogenetic analysis and further explores how the information of the conflicting phylogenetic signal can be used to detect and resolve hybrid accessions. The webinar showcases a novel bioinformatic workflow, HybPhaser, that can be used to detect and phase hybrids in target capture datasets and will provide the theoretical background and concepts behind the workflow.
This webinar is part of a series of webinars and workshops developed by the Genomics for Australian Plants (GAP) Initiative that focuses on the analysis of target capture sequence data. In addition to two public webinars, the GAP bioinformatics working group is offering training workshops in the use of newly developed and existing scripts in an integrated workflow to participants in the 2021 virtual Australasian Systematic Botany Society Conference.
The materials are shared under a Creative Commons 4.0 International agreement unless otherwise specified and were current at the time of the event.
**Files and materials included in this record:**
- Event metadata (PDF): Information about the event including, description, event URL, learning objectives, prerequisites, technical requirements etc.
- Index of training materials (PDF): List and description of all materials associated with this event including the name, format, location and a brief description of each file.
- Nauheimer_hybphaser_slides (PDF): Slides presented during the webinar
**Materials shared elsewhere:**
A recording of the webinar is available on the Australian BioCommons YouTube Channel: https://youtu.be/japXwTAhA5U
Melissa Burke (melissa@biocommons.org.au)
Nauheimer, Lars (orcid: 0000-0002-2847-0966)
Phylogenetics, Bioinformatics, Phylogeny, Genomics, Target capture sequencing
WEBINAR: Conflict in multi-gene datasets: why it happens and what to do about it - deep coalescence, paralogy and reticulation
This record includes training materials associated with the Australian BioCommons webinar ‘Conflict in multi-gene datasets: why it happens and what to do about it - deep coalescence, paralogy and reticulation’. This webinar took place on 20 May 2021.
Multi-gene datasets used in phylogenetic...
Keywords: Phylogenetics, Bioinformatics, Phylogeny, Genomics, Target capture sequencing
WEBINAR: Conflict in multi-gene datasets: why it happens and what to do about it - deep coalescence, paralogy and reticulation
https://zenodo.org/record/5104998
https://dresa.org.au/materials/webinar-conflict-in-multi-gene-datasets-why-it-happens-and-what-to-do-about-it-deep-coalescence-paralogy-and-reticulation
This record includes training materials associated with the Australian BioCommons webinar ‘Conflict in multi-gene datasets: why it happens and what to do about it - deep coalescence, paralogy and reticulation’. This webinar took place on 20 May 2021.
Multi-gene datasets used in phylogenetic analyses, such as those produced by the sequence capture or target enrichment used in the Genomics for Australian Plants: Australian Angiosperm Tree of Life project, often show discordance between individual gene trees and between gene and species trees. This webinar explores three different forms of discordance: deep coalescence, paralogy, and reticulation. In each case, it considers underlying biological processes, how discordance presents in the data, and what bioinformatic or phylogenetic approaches and tools are available to address these challenges. It covers Yang and Smith paralogy resolution and general information on options for phylogenetic analysis.
This webinar is part of a series of webinars and workshops developed by the Genomics for Australian Plants (GAP) Initiative that focused on the analysis of target capture sequence data. In addition to two public webinars, the GAP bioinformatics working group is offering training workshops in the use of newly developed and existing scripts in an integrated workflow to participants in the 2021 virtual Australasian Systematic Botany Society Conference.
The materials are shared under a Creative Commons 4.0 International agreement unless otherwise specified and were current at the time of the event.
**Files and materials included in this record:**
- Event metadata (PDF): Information about the event including, description, event URL, learning objectives, prerequisites, technical requirements etc.
- Index of training materials (PDF): List and description of all materials associated with this event including the name, format, location and a brief description of each file.
- Schmidt-Lebuhn - paralogy lineage sorting reticulation - slides (PDF): Slides presented during the webinar
**Materials shared elsewhere:**
A recording of the webinar is available on the Australian BioCommons YouTube Channel: https://youtu.be/1bw81q898z8
Melissa Burke (melissa@biocommons.org.au)
Schmidt-Lebuhn, Alexander (orcid: 0000-0002-7402-8941)
Phylogenetics, Bioinformatics, Phylogeny, Genomics, Target capture sequencing
DReSA: Project team reflections
This presentation provides thoughts and reflections from the Digital Research Skills Australaisa (DReSA) project team on DReSA. Team members highlight their perspectives on value propositions and benefits for their respective institutiosn/organisations and nationally, as well as individual...
Keywords: training events, training material, training repository, skilled workforce, digital research skills, digital research training, digital research, trainers, FAIR training
DReSA: Project team reflections
https://zenodo.org/record/5712129
https://dresa.org.au/materials/dresa-project-team-reflections
This presentation provides thoughts and reflections from the Digital Research Skills Australaisa (DReSA) project team on DReSA. Team members highlight their perspectives on value propositions and benefits for their respective institutiosn/organisations and nationally, as well as individual reflections on collaboration and working together on the project so far.
You can watch the video on YouTube here: https://youtu.be/qqH92itI8SI
contact@ardc.edu.au
Unsworth, Kathryn (orcid: 0000-0002-5407-9987)
Papaioannou, Anastasios (orcid: 0000-0002-8959-4559)
Backhaus, Ann (orcid: 0000-0002-9023-055X)
Vanichkina, Darya (orcid: 0000-0002-0406-164X)
Symon, Jon
Steel, Kay (orcid: 0000-0002-5720-1239)
Burke, Melissa (orcid: 0000-0002-5571-8664)
May, Nick
training events, training material, training repository, skilled workforce, digital research skills, digital research training, digital research, trainers, FAIR training