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Keywords: AI  or Phylogeny  or Health Data Australia 

Secondary use of clinical trials data in health research: A Practical Guide

This document presents a theoretical framework for the use of clinical trials and other health data for secondary research purposes, which was derived from research papers, consultation with stakeholders and the research community.  Four overall scenarios for data reuse were identified; scenario...

Keywords: Secondary Data Use, Clinical Trials, Training Material, HeSANDA, Health Data Australia, HDA

Secondary use of clinical trials data in health research: A Practical Guide https://dresa.org.au/materials/secondary-use-of-clinical-trials-data-in-health-research-a-practical-guide This document presents a theoretical framework for the use of clinical trials and other health data for secondary research purposes, which was derived from research papers, consultation with stakeholders and the research community.  Four overall scenarios for data reuse were identified; scenario 1: evidence synthesis, scenario 2: secondary analyses, scenario 3: reproducibility, replication and validation, and scenario 4: education and methods development. contact@ardc.edu.au Secondary Data Use, Clinical Trials, Training Material, HeSANDA, Health Data Australia, HDA
HeSANDA & Health Data Australia FAQ

This document provides answers to common questions about the Health Studies Australian National Data Asset (HeSANDA), and the Health Data Australia (HDA), including the usage of the health data platform, sharing, contributing and accessing clinital trails data, governance, and potential risks. 

Keywords: HeSANDA, Frequently asked Questions, Health Data Australia, training material

HeSANDA & Health Data Australia FAQ https://dresa.org.au/materials/hesanda-health-data-australia-faq This document provides answers to common questions about the Health Studies Australian National Data Asset (HeSANDA), and the Health Data Australia (HDA), including the usage of the health data platform, sharing, contributing and accessing clinital trails data, governance, and potential risks.  contact@ardc.edu.au Australian Research Data Commons (type: Editor) Australian Clinical Trials Alliance (type: Editor) Melbourne Academic Centre for Health (type: Editor) Mental Health Node (type: Editor) The Queensland Node (type: Editor) Sydney Health Partners Node (type: Editor) Western Australia Node (type: Editor) Monash University and Monash Partners Node (type: Editor) Health Translation South Australia (type: Editor) National Cancer Cooperative Trials Groups (type: Editor) Northern Australia Node (type: Editor) HeSANDA, Frequently asked Questions, Health Data Australia, training material
HeSANDA Monash Node User Guides

This guide developed by the HeSANDA Monash node provides an overview for users of Health Data Australia (HDA).
HDA helps researchers discover and access health data. HDA is a registry and does not store the data itself but provides descriptions of the data from data owners' publishing partners....

Keywords: Health Data Australia, health data, data request, HDA, HeSANDA, data access

HeSANDA Monash Node User Guides https://dresa.org.au/materials/hesanda-monash-node-user-guides This guide developed by the HeSANDA Monash node provides an overview for users of Health Data Australia (HDA). HDA helps researchers discover and access health data. HDA is a registry and does not store the data itself but provides descriptions of the data from data owners' publishing partners. Using HDA, researchers can search these descriptions, find data of use to do their research, then request access to it. The request will be sent to the owner of the data to review. Data owners receive email notifications about new data requests and can then log into the HDA Data Request platform to review the request and determine whether access can be granted and then respond to the researcher requesting access. If the request is approved, the owner arranges for the researcher to be given access to the data. The dataset descriptions (‘metadata’) contained on HDA help researchers understand the kinds of data that exist and assess whether a dataset may be of value to their research, without the need to actually access the data. In addition to metadata, data owners provide other documentation describing the data they hold, such as study protocols and data dictionaries. Using HDA, researchers can search for data, save their searches, submit and manage data requests. Amany.Gouda-Vossos@ardc.edu.au Health Data Australia, health data, data request, HDA, HeSANDA, data access
WEBINAR: Detection of and phasing of hybrid accessions in a target capture dataset

This record includes training materials associated with the Australian BioCommons webinar ‘Detection of and phasing of hybrid accessions in a target capture dataset’. This webinar took place on 10 June 2021.

Hybridisation plays an important role in evolution, leading to the exchange of genes...

Keywords: Phylogenetics, Bioinformatics, Phylogeny, Genomics, Target capture sequencing

WEBINAR: Detection of and phasing of hybrid accessions in a target capture dataset https://dresa.org.au/materials/webinar-detection-of-and-phasing-of-hybrid-accessions-in-a-target-capture-dataset-51cc7740-0da1-45f1-95de-f1a47f676053 This record includes training materials associated with the Australian BioCommons webinar ‘Detection of and phasing of hybrid accessions in a target capture dataset’. This webinar took place on 10 June 2021. Hybridisation plays an important role in evolution, leading to the exchange of genes between species and, in some cases, generate new lineages. The use of molecular methods has revealed the frequency and importance of reticulation events is higher than previously thought and this insight continues with the ongoing development of phylogenomic methods that allow novel insights into the role and extent of hybridisation. Hybrids notoriously provide challenges for the reconstruction of evolutionary relationships, as they contain conflicting genetic information from their divergent parental lineages. However, this also provides the opportunity to gain insights into the origin of hybrids (including autopolyploids). This webinar explores some of the challenges and opportunities that occur when hybrids are included in a target capture sequence dataset. In particular, it describes the impact of hybrid accessions on sequence assembly and phylogenetic analysis and further explores how the information of the conflicting phylogenetic signal can be used to detect and resolve hybrid accessions. The webinar showcases a novel bioinformatic workflow, HybPhaser, that can be used to detect and phase hybrids in target capture datasets and will provide the theoretical background and concepts behind the workflow. This webinar is part of a series of webinars and workshops developed by the Genomics for Australian Plants (GAP) Initiative that focuses on the analysis of target capture sequence data. In addition to two public webinars, the GAP bioinformatics working group is offering training workshops in the use of newly developed and existing scripts in an integrated workflow to participants in the 2021 virtual Australasian Systematic Botany Society Conference. The materials are shared under a Creative Commons 4.0 International agreement unless otherwise specified and were current at the time of the event. Files and materials included in this record: Event metadata (PDF): Information about the event including, description, event URL, learning objectives, prerequisites, technical requirements etc. Index of training materials (PDF): List and description of all materials associated with this event including the name, format, location and a brief description of each file. Nauheimer_hybphaser_slides (PDF): Slides presented during the webinar Materials shared elsewhere: A recording of the webinar is available on the Australian BioCommons YouTube Channel: https://youtu.be/japXwTAhA5U Melissa Burke (melissa@biocommons.org.au) Phylogenetics, Bioinformatics, Phylogeny, Genomics, Target capture sequencing
WEBINAR: Conflict in multi-gene datasets: why it happens and what to do about it - deep coalescence, paralogy and reticulation

This record includes training materials associated with the Australian BioCommons webinar ‘Conflict in multi-gene datasets: why it happens and what to do about it - deep coalescence, paralogy and reticulation’. This webinar took place on 20 May 2021.

Multi-gene datasets used in phylogenetic...

Keywords: Phylogenetics, Bioinformatics, Phylogeny, Genomics, Target capture sequencing

WEBINAR: Conflict in multi-gene datasets: why it happens and what to do about it - deep coalescence, paralogy and reticulation https://dresa.org.au/materials/webinar-conflict-in-multi-gene-datasets-why-it-happens-and-what-to-do-about-it-deep-coalescence-paralogy-and-reticulation-a6743550-b904-45e1-9635-4e481ee8f739 This record includes training materials associated with the Australian BioCommons webinar ‘Conflict in multi-gene datasets: why it happens and what to do about it - deep coalescence, paralogy and reticulation’. This webinar took place on 20 May 2021. Multi-gene datasets used in phylogenetic analyses, such as those produced by the sequence capture or target enrichment used in the Genomics for Australian Plants: Australian Angiosperm Tree of Life project, often show discordance between individual gene trees and between gene and species trees. This webinar explores three different forms of discordance: deep coalescence, paralogy, and reticulation. In each case, it considers underlying biological processes, how discordance presents in the data, and what bioinformatic or phylogenetic approaches and tools are available to address these challenges. It covers Yang and Smith paralogy resolution and general information on options for phylogenetic analysis. This webinar is part of a series of webinars and workshops developed by the Genomics for Australian Plants (GAP) Initiative that focused on the analysis of target capture sequence data. In addition to two public webinars, the GAP bioinformatics working group is offering training workshops in the use of newly developed and existing scripts in an integrated workflow to participants in the 2021 virtual Australasian Systematic Botany Society Conference. The materials are shared under a Creative Commons 4.0 International agreement unless otherwise specified and were current at the time of the event. Files and materials included in this record: Event metadata (PDF): Information about the event including, description, event URL, learning objectives, prerequisites, technical requirements etc. Index of training materials (PDF): List and description of all materials associated with this event including the name, format, location and a brief description of each file. Schmidt-Lebuhn - paralogy lineage sorting reticulation - slides (PDF): Slides presented during the webinar   Materials shared elsewhere: A recording of the webinar is available on the Australian BioCommons YouTube Channel: https://youtu.be/1bw81q898z8 Melissa Burke (melissa@biocommons.org.au) Phylogenetics, Bioinformatics, Phylogeny, Genomics, Target capture sequencing
WEBINAR: AlphaFold: what's in it for me?

This record includes training materials associated with the Australian BioCommons webinar ‘WEBINAR: AlphaFold: what’s in it for me?’. This webinar took place on 18 April 2023.

Event description 

AlphaFold has taken the scientific world by storm with the ability to accurately predict the...

Keywords: Bioinformatics, Machine Learning, Structural Biology, Proteins, Drug discovery, AlphaFold, AI, Artificial Intelligence, Deep learning

WEBINAR: AlphaFold: what's in it for me? https://dresa.org.au/materials/webinar-alphafold-what-s-in-it-for-me-4d1ea222-4240-4b68-b9ae-7769ac664ee0 This record includes training materials associated with the Australian BioCommons webinar ‘WEBINAR: AlphaFold: what’s in it for me?’. This webinar took place on 18 April 2023. Event description  AlphaFold has taken the scientific world by storm with the ability to accurately predict the structure of any protein in minutes using artificial intelligence (AI). From drug discovery to enzymes that degrade plastics, this promises to speed up and fundamentally change the way that protein structures are used in biological research.  Beyond the hype, what does this mean for structural biology as a field (and as a career)? Dr Craig Morton, Drug Discovery Lead at the CSIRO, is an early adopter of AlphaFold and has decades of expertise in protein structure / function, protein modelling, protein – ligand interactions and computational small molecule drug discovery, with particular interest in anti-infective agents for the treatment of bacterial and viral diseases. Craig joins this webinar to share his perspective on the implications of AlphaFold for science and structural biology. He will give an overview of how AlphaFold works, ways to access AlphaFold, and some examples of how it can be used for protein structure/function analysis. Materials are shared under a Creative Commons Attribution 4.0 International agreement unless otherwise specified and were current at the time of the event. Files and materials included in this record: Event metadata (PDF): Information about the event including, description, event URL, learning objectives, prerequisites, technical requirements etc. Index of training materials (PDF): List and description of all materials associated with this event including the name, format, location and a brief description of each file. Materials shared elsewhere: A recording of this webinar is available on the Australian BioCommons YouTube Channel: https://youtu.be/4ytn2_AiH8s Melissa Burke (melissa@biocommons.org.au) Bioinformatics, Machine Learning, Structural Biology, Proteins, Drug discovery, AlphaFold, AI, Artificial Intelligence, Deep learning
Accelerating skills development in Data science and AI at scale

At the Monash Data Science and AI  platform, we believe that upskilling our research community and building a workforce with data science skills are key to accelerating the application of data science in research. To achieve this, we create and leverage new and existing training capabilities...

Keywords: AI, machine learning, eresearch skills, training, train the trainer, volunteer instructors, training partnerships, training material

Accelerating skills development in Data science and AI at scale https://dresa.org.au/materials/accelerating-skills-development-in-data-science-and-ai-at-scale-2d8a65fa-f96e-44ad-a026-cfae3f38d128 At the Monash Data Science and AI  platform, we believe that upskilling our research community and building a workforce with data science skills are key to accelerating the application of data science in research. To achieve this, we create and leverage new and existing training capabilities within and outside Monash University. In this talk, we will discuss the principles and purpose of establishing collaborative models to accelerate skills development at scale. We will talk about our approach to identifying gaps in the existing skills and training available in data science, key areas of interest as identified by the research community and various sources of training available in the marketplace. We will provide insights into the collaborations we currently have and intend to develop in the future within the university and also nationally. The talk will also cover our approach as outlined below •        Combined survey of gaps in skills and trainings for Data science and AI •        Provide seats to partners •        Share associate instructors/helpers/volunteers •        Develop combined training materials •        Publish a repository of open source trainings •        Train the trainer activities •        Establish a network of volunteers to deliver trainings at their local regions Industry plays a significant role in making some invaluable training available to the research community either through self learning platforms like AWS Machine Learning University or Instructor led courses like NVIDIA Deep Learning Institute. We will discuss how we leverage our partnerships with Industry to bring these trainings to our research community. Finally, we will discuss how we map our training to the ARDC skills roadmap and how the ARDC platforms project “Environments to accelerate Machine Learning based Discovery” has enabled collaboration between Monash University and University of Queensland to develop and deliver training together. contact@ardc.edu.au AI, machine learning, eresearch skills, training, train the trainer, volunteer instructors, training partnerships, training material
Monash University - University of Queensland training partnership in Data science and AI

We describe the peer network exchange for training that has been recently created via an ARDC funded partnership between Monash University and Universities of Queensland under the umbrella of the Queensland Cyber Infrastructure Foundation (QCIF). As part of a training program in machine learning,...

Keywords: data skills, training partnerships, data science, AI, training material

Monash University - University of Queensland training partnership in Data science and AI https://dresa.org.au/materials/monash-university-university-of-queensland-training-partnership-in-data-science-and-ai-8082bf73-d20f-4214-ad8c-95123e25a36c We describe the peer network exchange for training that has been recently created via an ARDC funded partnership between Monash University and Universities of Queensland under the umbrella of the Queensland Cyber Infrastructure Foundation (QCIF). As part of a training program in machine learning, visualisation, and computing tools, we have established a series of over 20 workshops over the year where either Monash or QCIF hosts the event for some 20-40 of their researchers and students, while some 5 places are offered to participants from the other institution. In the longer term we aim to share material developed at one institution and have trainers present it at the other. In this talk we will describe the many benefits we have found to this approach including access to a wider range of expertise in several rapidly developing fields, upskilling of trainers, faster identification of emerging training needs, and peer learning for trainers. contact@ardc.edu.au data skills, training partnerships, data science, AI, training material
HeSANDA Monash Node Workshop Content

Slide presentation for a HeSANDA workshop delivered on January 1, 2023, which provides the audience with a broad understanding of the HeSANDA program, including Health Data Australia (HDA). 
 
What is HeSANDA:
The Health Studies Australian Data Asset (HeSANDA) is a national program that makes...

Keywords: health data, clinical trials, HeSANDA, Health Data Australia

HeSANDA Monash Node Workshop Content https://dresa.org.au/materials/hesanda-monash-node-workshop-content Slide presentation for a HeSANDA workshop delivered on January 1, 2023, which provides the audience with a broad understanding of the HeSANDA program, including Health Data Australia (HDA).    What is HeSANDA: The Health Studies Australian Data Asset (HeSANDA) is a national program that makes health and medical research data easier to find. It facilitates access, sharing and reuse of research data. This results in a reduction in research waste, improvements in researcher collaboration, and an opppotunity ti answer new research questions. It aims to support more efficitent and effective research to help improve health outcome.   Amany.Gouda-Vossos@ardc.edu.au health data, clinical trials, HeSANDA, Health Data Australia